Understanding the genetic drivers behind tumorigenesis is critical for the development of cancer therapeutics. Utilizing extensive genomic characterization technologies Scientists at CrownBio now make that data accessible to the wider scientific community OncoExpress(TM) provides a simple, fast way to find all relevant models across multiple platform types. the application Collates data from three databases,HuBase, MuBase and XenoBase.
HuBase™A unique database containing the complete genomic annotation of our HuPrime PDX models:
MuBase®A database containing information for CrownBio’s immuno-oncology murine efficacy platforms:
Syngeneic tumor modelsMurine allograft models, MuPrimeGEMMHumanized HuGEMM mouse models.
Available data includes; proteomic, and pharmacological profiles completed for these models to help identify the most suitable models for your studies.
XenoBase®The world’s first database for cell lines and Cell Line Derived Xenograft models, collating data from over 1,000 tumor cell lines. XenoBase combines:Public profiling dataexpression, copy number, and mutationProprietary pharmacology data